Sertindole → HCID 11742071, compound

HRID 986088Notes

Reaction equation

HRID 986088 reaction equation
Cl[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:16]=[CH:15][C:14]([F:17])=[CH:13][CH:12]=1)[CH:6]=[C:5]2[CH:18]1[CH2:23][CH2:22][N:21]([CH2:24][CH2:25][N:26]2[CH2:30][CH2:29][NH:28][C:27]2=[O:31])[CH2:20][CH2:19]1.C([O-])(=O)/C=C\C([O-])=O>>[F:17][C:14]1[CH:15]=[CH:16][C:11]([N:7]2[C:8]3[C:4](=[CH:3][CH:2]=[CH:10][CH:9]=3)[C:5]([CH:18]3[CH2:23][CH2:22][N:21]([CH2:24][CH2:25][N:26]4[CH2:30][CH2:29][NH:28][C:27]4=[O:31])[CH2:20][CH2:19]3)=[CH:6]2)=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 60149SertindoleHCID 5288227Maleate(2-)

Product 1

HCID 11742071HCID 11742071, compound

Procedure

5-Chloro-1-(4'-fluorophenyl)-3-(1-(2-imidazolidinon-1-ylethyl)-4-piperidyl)-1H-indole, maleate. (Lu 23-174). M.p. 155°-160° C.

Sources & evidence

ORD record
ord-cecfedb1168c41ecaab40c016b48e3ac
Source dataset
uspto-grants-1987_12
Patent number
US04710500

Reaction notes

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