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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 986214Generated: November 1, 2026

Sodium Hydroxide → (+/-)-dihydro-3-[(1-carboxy-3-phenylpropyl)amino]-4-oxo-1,5-benzothiazepine-5(2H)-acetic acid

https://huagongshe.com/reaction/986214

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant(+/-)-Dihydro-3-[[1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-4-oxo-1,5-benzothiazepine-5(2H)acetic acid, ethyl esterHCID 86741917—
Product(+/-)-dihydro-3-[(1-carboxy-3-phenylpropyl)amino]-4-oxo-1,5-benzothiazepine-5(2H)-acetic acidHCID 86741918—

Reaction Steps

The diethyl ester product from part (f) is treated with sodium hydroxide according to the procedure of Example 1(h) to yield (±)-dihydro-3-[(1-carboxy-3-phenylpropyl)amino]-4-oxo-1,5-benzothiazepine-5(2H)-acetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04711884
Source datasetuspto-grants-1987_12
ORD IDord-003f582099f14af180bd63243f03c87c
Source noteuspto-grants-1987_12