Thionyl Chloride → HCID 13336368, compound

HRID 986269Notes

Reaction equation

HRID 986269 reaction equation
[C:1]1([C:7]2[CH:8]=[C:9]([C:17](O)=[O:18])[C:10]3[C:15]([CH:16]=2)=[CH:14][CH:13]=[CH:12][CH:11]=3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(Cl)(Cl)=O.[CH3:24][NH:25][CH:26]([CH2:28][CH3:29])[CH3:27]>N1C=CC=CC=1>[CH3:24][N:25]([CH:26]([CH3:27])[CH2:28][CH3:29])[C:17]([C:9]1[C:10]2[C:15](=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH:16]=[C:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH:8]=1)=[O:18]

Participants

5

Reactant 3

HCID 24386Thionyl ChlorideHCID 111026N-Methyl-2-butanamineHCID 105625053-phenylnaphthalene-1-carboxylic Acid

Product 1

HCID 13336368HCID 13336368, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The procedure of Example 20 is followed using 3-phenylnaphthalene-1-carboxylic acid (4.3 g), thionyl chloride (20 ml) and N-methylbut-2-ylamine (1.5 g) in pyridine (20 ml) as the starting materials. After recrystallisation from petroleum ether, N-methyl-N-(1-methylpropyl)-3-phenylnaphthalene-1-carboxamide (2.8 g), melting at 125° C., is obtained.

Workup

  1. customAfter recrystallisation from petroleum ether, N-methyl-N-(1-methylpropyl)-3-phenylnaphthalene-1-carboxamide (2.8 g), melting at 125° C.
  2. customis obtained

Sources & evidence

ORD record
ord-4bca470a0a984ef38002b054ad2a766a
Source dataset
uspto-grants-1987_12
Patent number
US04711890

Reaction notes

Loading…