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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 986271Generated: October 30, 2026

Pyrrolidine → HCID 13336371, compound

https://huagongshe.com/reaction/986271

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
ReactantHCID 20158356HCID 20158356—
ReactantButyllithiumHCID 178418339—
SolventTetrahydrofuranHCID 8028—
SolventHexaneHCID 8058—
ProductHCID 13336371HCID 13336371—

Reaction Steps

The procedure of Example 24 is followed using ehtyl 2-phenylquinazoline-4-carboxylate (3 g), pyrrolidine (3 ml), a 1.6M solution of butyllithium in hexane (15 ml) and tetrahydrofuran (25 ml) as the starting materials. After recrystallisation from ethanol, 1-[(2-phenylquinazolin-4-yl)-carbonyl]-pyrrolidine (2.1 g), melting at 153° C., is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04711890
Source datasetuspto-grants-1987_12
ORD IDord-076c5b096b8041b39555ae4d6ca56a49
Source noteuspto-grants-1987_12