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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 986273Generated: November 1, 2026

Morpholine → HCID 13336373, compound

https://huagongshe.com/reaction/986273

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantHCID 20158356HCID 20158356—
ReactantButyllithiumHCID 178418339—
SolventTetrahydrofuranHCID 8028—
SolventHexaneHCID 8058—
ProductHCID 13336373HCID 13336373—

Reaction Steps

The procedure of Example 24 is followed using ethyl 2-phenylquinazoline-4-carboxylate (3.1 g), morpholine (2 ml), a 1.6M solution of butyllithium in hexane (15 ml) and tetrahydrofuran (20 ml) as the starting materials. After recrystallisation from ethanol, 4-[(2-phenylquinazolin-4-yl)-carbonyl]-morpholine (3 g), melting at 148° C., is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04711890
Source datasetuspto-grants-1987_12
ORD IDord-0afad2279af04815a1098cde6c583236
Source noteuspto-grants-1987_12