HCID 629065, compound → HCID 13336366, compound

HRID 986290Notes

Reaction equation

HRID 986290 reaction equation
[C:1]1([C:7]2[CH:16]=[C:15]([C:17]([OH:19])=O)[C:14]3[C:9](=[C:10]([C:20]([F:23])([F:22])[F:21])[CH:11]=[CH:12][CH:13]=3)[N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:24]1([C:30]2N=C(C(N3CCCCCC3)=O)C3[C:32](=[CH:33]C=CC=3)[N:31]=2)C=CC=CC=1>>[CH2:30]([N:31]([CH2:32][CH3:33])[C:17]([C:15]1[C:14]2[C:9](=[C:10]([C:20]([F:21])([F:23])[F:22])[CH:11]=[CH:12][CH:13]=2)[N:8]=[C:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH:16]=1)=[O:19])[CH3:24]

Participants

3

Reactant 2

HCID 629065HCID 629065, compoundHCID 13336375HCID 13336375, compound

Product 1

HCID 13336366HCID 13336366, compound

Procedure

The 2-phenyl-8-trifluoromethylquinoline-4-carboxylic acid can be prepared by the process described by D. W. BOYKIN et al., J. Med. Chem., 11 (2), 273-277 (1968).

Sources & evidence

ORD record
ord-6cbf45341ed24aefb82fce42cb2356f7
Source dataset
uspto-grants-1987_12
Patent number
US04711890

Reaction notes

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