Cornforth reagent → HCID 20158426, compound

Participants

Reaction Steps

1.9 g (7.6 mmoles) of 3,5-dihydroxy-3-(4-phenoxybutyl)cyclopentene was dissolved in 15 ml of dichloromethane, and at 0° C. 5.7 g (15 mmoles) of pyridinium dichromate was added. The mixture was stirred at room temperature for 2 hours. The reaction mixture was diluted with 200 ml of ether, and filtered through Celite. After concentration, 1.32 g (71%) of 4-hydroxy-4-(4-phenoxybutyl)-2-cyclopentenone was obtained.

Provenance & Evidence