Imidazole → HCID 21400465, compound

HRID 986346Notes

Reaction equation

HRID 986346 reaction equation
[C:1](=[O:11])(SC)[S:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.N1C=CN=[CH:13]1>C(O)CO>[C:3]1([S:2][CH:1]([OH:11])[CH3:13])[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 795ImidazoleHCID 572988HCID 572988, compound

Product 1

HCID 21400465HCID 21400465, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 174Ethylene GlycolSolvent2×

Conditions

Temperature
160 °C

Procedure

S-phenyl S-methyl dithiocarbonate prepared as described in Example 3 (5 g), ethylene glycol (5 ml), and imidazole (0.1 g) were placed in a stirred flask and heated to 160° C. for 10 hours. At this time, the major component (excepting ethylene glycol) was identified by g.c. comparison with an authentic sample as phenylmercaptoethanol (g.c. suggested over 90 percent yield).

Workup

  1. customwere placed in a stirred flask

Sources & evidence

ORD record
ord-838c5a5f265449b38e3f5c0811bd1f3d
Source dataset
uspto-grants-1987_12
Patent number
US04711967

Reaction notes

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