Potassium Hydroxide → HCID 20157319, compound

HRID 986373Notes

Reaction equation

HRID 986373 reaction equation
[F:1][C:2]([F:27])([F:26])[C:3]1[CH:4]=[C:5]([CH:23]=[CH:24][CH:25]=1)[CH2:6][O:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]/[CH:14]=[CH:15]/[CH:16]=[CH:17]/[C:18]([O:20]CC)=[O:19].[OH-].[K+]>O.C(O)C>[F:1][C:2]([F:26])([F:27])[C:3]1[CH:4]=[C:5]([CH:23]=[CH:24][CH:25]=1)[CH2:6][O:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]/[CH:14]=[CH:15]/[CH:16]=[CH:17]/[C:18]([OH:20])=[O:19]

Participants

5

Reactant 2

HCID 14797Potassium HydroxideHCID 20157330HCID 20157330, compound

Product 1

HCID 20157319HCID 20157319, compoundYield 63%

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

The product of step (c) (1.74 g, 4.5 mmol) was hydrolysed with potassium hydroxide (0.88 g) in water (20 mL) and ethanol (60 mL) at room temperature over 18 hours to give 1.0 g (63% of theory) of 11-(3'trifluoromethylbenzyloxy)-(2E,4E)-undecadienoic acid.

Sources & evidence

ORD record
ord-55fb0f8aecc34ac2aa73803dd5e92181
Source dataset
uspto-grants-1987_12
Patent number
US04713200

Reaction notes

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