Hydrazine hydrate (1:1) → HCID 14032921, compound

Participants

Reaction Steps

A mixture of 7 g of 5-ethoxycarbonylaminoacetyl-6-methylimidazo[2,1-b]thiazole, 100 ml of ethanol and 8 ml of 100% hydrazine hydrate is refluxed under heating for 2 days. After cooling, crystals are collected by filtration and recrystallized from a mixed solvent of chloroform and methanol to give 3.4 g of 6-(6-methylimidazo[2,1-b]thiazol-5-yl)-4,5-dihydro-2H-1,2,4 triazin-3-one as white crystals, melting at 293°-295° C. with decomposition.

Provenance & Evidence