Monobenzone → 3-[4-(Benzyloxy)phenoxy]butan-2-one

HRID 986483Notes

Reaction equation

HRID 986483 reaction equation
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH:17]([CH3:21])[C:18](=[O:20])[CH3:19]>>[CH2:1]([O:8][C:9]1[CH:10]=[CH:11][C:12]([O:15][CH:17]([CH3:21])[C:18](=[O:20])[CH3:19])=[CH:13][CH:14]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 7638MonobenzoneHCID 200263-Chloro-2-butanone

Product 1

HCID 140932993-[4-(Benzyloxy)phenoxy]butan-2-one

Procedure

The process as indicated in Example 1 was repeated a number of times, utilizing molar quantities each of 4-benzyloxyphenol and 3-chloro-2-butanone, and varying quantities of base, catalyst and solvent, as well as differing times and temperatures.

Sources & evidence

ORD record
ord-170b881b55674f57bdb9a5dc69982a6f
Source dataset
uspto-grants-1987_12
Patent number
US04713471

Reaction notes

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