HCID 178527786, compound → HCID 178477908, compound

HRID 986508Notes

Reaction equation

HRID 986508 reaction equation
[Cl:1][C:2]1[CH:11]=[CH:10][C:9]2[N:8]=[C:7](S)[N:6]3[N:13]=[C:14]([C:16]4[O:17][CH:18]=[CH:19][CH:20]=4)[N:15]=[C:5]3[C:4]=2[CH:3]=1>NC1C=CC=CC=1>[Cl:1][C:2]1[CH:11]=[CH:10][C:9]2[NH:8][C:7](=[N:8][C:9]3[CH:10]=[CH:11][CH:2]=[CH:3][CH:4]=3)[N:6]3[N:13]=[C:14]([C:16]4[O:17][CH:18]=[CH:19][CH:20]=4)[N:15]=[C:5]3[C:4]=2[CH:3]=1

Participants

3

Reactant 1

HCID 178527786HCID 178527786, compound

Product 1

HCID 178477908HCID 178477908, compound

Reagents, catalysts & solvents 1

HCID 6115AnilineSolvent

Procedure

A mixture of 9-chloro-2-(2-furyl)-5-mercapto[1,2,4]triazolo[1,5-c]quinazoline (5.6 g) and aniline (40 ml) is stirred at 150° for 66 hours under nitrogen. The mixture is heated on a rotary evaporator under water pump vacuum to remove residual aniline and recrystallized from aqueous ethanol to afford pure 9-chloro-2-(2-furyl)-5-phenylimino-5,6-dihydro-[1,2,4]triazolo[1,5-c]quinazoline, mp 231°-233°.

Workup

  1. temperatureThe mixture is heated on a rotary evaporator under water
  2. customto remove residual aniline
  3. customrecrystallized from aqueous ethanol

Sources & evidence

ORD record
ord-a79ac80a6c72436388f4e26c9da15422
Source dataset
uspto-grants-1987_12
Patent number
US04713383

Reaction notes

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