HCID 14031946, compound → HCID 178456947, compound

HRID 986509Notes

Reaction equation

HRID 986509 reaction equation
[Cl:1][C:2]1[CH:11]=[CH:10][C:9]2[N:8]=[C:7](SC)[N:6]3[N:14]=[C:15]([C:17]4[O:18][CH:19]=[CH:20][CH:21]=4)[N:16]=[C:5]3[C:4]=2[CH:3]=1>C(N)(C)C>[Cl:1][C:2]1[CH:11]=[CH:10][C:9]2[NH:8][C:7](=[N:8][CH:9]([CH3:10])[CH3:4])[N:6]3[N:14]=[C:15]([C:17]4[O:18][CH:19]=[CH:20][CH:21]=4)[N:16]=[C:5]3[C:4]=2[CH:3]=1

Participants

3

Reactant 1

HCID 14031946HCID 14031946, compound

Product 1

HCID 178456947HCID 178456947, compound

Reagents, catalysts & solvents 1

HCID 6363IsopropylamineSolvent

Procedure

As in Example 37, 9-chloro-2-(2-furyl)-5-methylthio[1,2,4]triazolo[1,5-c]quinazoline (1.06 g) is reacted in a stainless steel pressure vessel with isopropylamine (50 ml) at 150° (external temperature) for 6 hours to afford 9-chloro-2-(2-furyl)-5-isopropylimino-5,6-dihydro-[1,2,4]triazolo[1,5-c]quinazoline, which is purified by ethanol recrystallization, mp. 140°-141°.

Sources & evidence

ORD record
ord-7977ddb4976b4663813f658acd5be555
Source dataset
uspto-grants-1987_12
Patent number
US04713383

Reaction notes

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