Ammonia → HCID 178509081, compound

Participants

Reaction Steps

To a solution of 4.9 g of 2-(5-bromo-2-furyl)-9-chloro-5-thiocyanato[1,2,4]triazolo[1,5-c]quinazoline in 80 cc of tetrahydrofuran is added gaseous ammonia under ice cooling over 1.3 hr. The precipitate which forms is collected washed with tetrahydrofuran, recrystallized from N,N-dimethyl acetamide and dried under high vacuum at 100° to afford pure 2-(5-bromo-2-furyl)-9-chloro-5-imino-5,6-dihydro[1,2,4]triazolo[1,5-c]quinazoline, mp 282°-283°.

Provenance & Evidence