Sodium Hydroxide → HCID 23705017, compound

HRID 986581Notes

Reaction equation

HRID 986581 reaction equation
[CH3:1][N:2]1[C:10]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:9][C:8](=[O:17])[C:4]([C:5]([OH:7])=[O:6])=[C:3]1[CH2:18][CH2:19][CH3:20].[OH-].[Na+:22]>CO>[CH3:1][N:2]1[C:10]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:9][C:8](=[O:17])[C:4]([C:5]([O-:7])=[O:6])=[C:3]1[CH2:18][CH2:19][CH3:20].[Na+:22]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 14075324HCID 14075324, compound

Product 1

HCID 23705017HCID 23705017, compoundYield 97%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2.1 g (0.0067 mol) of 1-methyl-6-phenyl-2-propyl-4-oxonicotinic acid is suspended in 50 ml of methanol and to it there is added 0.295 g (0.0074 mol) of sodium hydroxide pellets. The solution is concentrated in vacuo to afford 1.9 g (97% yield) of product.

Workup

  1. concentrationThe solution is concentrated in vacuo

Sources & evidence

ORD record
ord-a2bf873ba07d4a89995b5e629f36b8bd
Source dataset
uspto-grants-1987_12
Patent number
US04714492

Reaction notes

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