Isopropylamide → D-Alanine 1-Adamantyl Amide

HRID 986618Notes

Reaction equation

HRID 986618 reaction equation
[C:1]12([NH:11][C:12](=[O:26])[C@@H:13]([CH3:25])[NH:14]C(OCC3C=CC=CC=3)=O)[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.C([NH-])(C)C>>[C:1]12([NH:11][C:12](=[O:26])[C@@H:13]([CH3:25])[NH2:14])[CH2:10][CH:5]3[CH2:4][CH:3]([CH2:9][CH:7]([CH2:6]3)[CH2:8]1)[CH2:2]2

Participants

3

Reactant 2

HCID 18378000IsopropylamideHCID 18611109N-Benzyloxycarbonyl-D-alanine 1-Adamantyl Amide

Product 1

HCID 18611099D-Alanine 1-Adamantyl Amide

Procedure

N-Benzyloxycarbonyl-D-alanine 1-adamantyl amide is hydrogenated by the precedure as described for the isopropyl amide.

Sources & evidence

ORD record
ord-48f6db033ade4c409816d20367cf7457
Source dataset
uspto-grants-1987_12
Patent number
US04714619

Reaction notes

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