Fluoroacetyl chloride → HCID 13376459, compound

HRID 986658Notes

Reaction equation

HRID 986658 reaction equation
[NH2:1][C:2]1[CH:19]=[CH:18][C:17]([N+:20]([O-:22])=[O:21])=[CH:16][C:3]=1[C:4]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH3:14])=[CH:9][C:8]=1[CH3:15])=[O:5].[F:23][CH2:24][C:25](Cl)=[O:26]>N1C=CC=CC=1>[F:23][CH2:24][C:25]([NH:1][C:2]1[CH:19]=[CH:18][C:17]([N+:20]([O-:22])=[O:21])=[CH:16][C:3]=1[C:4]([NH:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH3:14])=[CH:9][C:8]=1[CH3:15])=[O:5])=[O:26]

Participants

4

Reactant 2

HCID 9663Fluoroacetyl chlorideHCID 13376452HCID 13376452, compound

Product 1

HCID 13376459HCID 13376459, compoundYield 86.9%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

4.8 g of N-(2-amino-5-nitrobenzoyl)-2-methyl-4-methoxyaniline, 1.9 g of pyridine and 2.32 g of fluoroacetyl chloride are treated in the same manner as described in Example 1-(1), whereby 5.0 g of N-(2-fluoroacetamido-5-nitrobenzoyl)-2-methyl-4-methoxyaniline are obtained as colorless needles.

Sources & evidence

ORD record
ord-0edc20b117e041978a0da5f5fe7a3f25
Source dataset
uspto-grants-1987_12
Patent number
US04714702

Reaction notes

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