Boron trifluoride etherate → HCID 13376467, compound

HRID 986659Notes

Reaction equation

HRID 986659 reaction equation
[F:1][CH2:2][C:3]([NH:5][C:6]1[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][C:7]=1[C:8]([NH:10][C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][C:12]=1[CH3:19])=[O:9])=O.B(F)(F)F.CCOCC>C(O)(=O)C>[F:1][CH2:2][C:3]1[N:10]([C:11]2[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][C:12]=2[CH3:19])[C:8](=[O:9])[C:7]2[C:6](=[CH:23][CH:22]=[C:21]([N+:24]([O-:26])=[O:25])[CH:20]=2)[N:5]=1

Participants

4

Reactant 2

HCID 8000Boron trifluoride etherateHCID 13376459HCID 13376459, compound

Product 1

HCID 13376467HCID 13376467, compoundYield 86.8%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

4.0 g of N-(2-fluoroacetamido-5-nitrobenzoyl)-2-methyl-4-methoxyaniline, 3.5 g of boron trifluoride etherate and 30 ml of acetic acid are treated in the same manner as described in Example 1-(2)l, whereby 3.3 g of 2-fluoromethyl-3-(2-methyl-4-methoxyphenyl)-6-nitro-4(3H)-quinazolinone are obtained as yellow prisms.

Sources & evidence

ORD record
ord-b70708552ca7402e8f8fd44dcf4eb1a8
Source dataset
uspto-grants-1987_12
Patent number
US04714702

Reaction notes

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