HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromobenzoic acid → 4-Bromobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromobenzoic acid | HCID 11464 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Catalyst | Dichloromethane | HCID 6344 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Bromobenzoyl chloride | HCID 68515 | — |
Reaction Steps
A mixture of 100 g (0.497 mole) of 4-bromobenzoic acid and 100 g of thionyl chloride in 300 ml of dichloromethane containing a few drops of N,N-dimethylformamide was heated at reflux for two days. The low boiling liquid were then removed by evaporation, and the remaining liquid was distilled to provide 4-bromobenzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04714776 |
| Source dataset | uspto-grants-1987_12 |
| ORD ID | ord-d76c56fe2dfc4b109a0976986d1fe7a9 |
| Source note | uspto-grants-1987_12 |