HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(1,3-Benzothiazol-2-yl)acetonitrile → alpha-[Benzthiazol-2-yl]-alpha-oximino-acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(1,3-Benzothiazol-2-yl)acetonitrile | HCID 342465 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Water | HCID 962 | — |
| Product | alpha-[Benzthiazol-2-yl]-alpha-oximino-acetonitrile | HCID 686137 | — |
Reaction Steps
A solution of 7.8 g (0.1 mol) of NaNO2 in 20 ml of water is added dropwise at room temperature to 17.4 g (0.1 mol) of 2-cyanomethyl-benzthiazole in 50 ml of glacial acetic acid. The end product is filtered off after 2 hours and washed with water: 19.5 g (96% of theory), melting point >170° (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04715883 |
| Source dataset | uspto-grants-1987_12 |
| ORD ID | ord-e55421eabc4f435d97086973fdfc5dd0 |
| Source note | uspto-grants-1987_12 |