HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 1,4-Dihydroxy-5,8-bis[2-(2-hydroxypropylamino)ethylamino]anthracene-9,10-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 1,4-Dihydroxy-5,8-bis[2-(2-hydroxypropylamino)ethylamino]anthraquinone dihydrochloride | HCID 12519551 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1,4-Dihydroxy-5,8-bis[2-(2-hydroxypropylamino)ethylamino]anthracene-9,10-dione | HCID 433060 | — |
Reaction Steps
A mixture of 6.0 g of 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxypropyl)amino]ethyl]amino]anthraquinone dihydrochloride (prepared as described in Example 32 of U.S. Pat. No. 4,197,249) and 60 ml of methanol is treated with ammonia gas according to the procedure of Example 1 to give the corresponding free base, 1,4-dihydroxy-5,8- bis[[2-[(2-hydroxypropyl)amino]ethyl]amino]-anthraquinone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04715993 |
| Source dataset | uspto-grants-1987_12 |
| ORD ID | ord-1ccae82393d04ee1ae6827b928102ad3 |
| Source note | uspto-grants-1987_12 |