HCID 19880136, compound → HCID 19880121, compound

HRID 986732Notes

Reaction equation

HRID 986732 reaction equation
COC(=O)C(CCCC1CCCCC1)=C.C[O:17][P:18]([CH:35]([NH:37]C(OCC1C=CC=CC=1)=O)[CH3:36])([CH2:20][CH:21]([C:31]([O:33]C)=[O:32])[CH2:22][CH2:23][CH2:24][CH:25]1[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1)=[O:19]>>[NH2:37][CH:35]([P:18]([CH2:20][CH:21]([C:31]([OH:33])=[O:32])[CH2:22][CH2:23][CH2:24][CH:25]1[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1)(=[O:17])[OH:19])[CH3:36]

Participants

3

Reactant 2

HCID 19880136HCID 19880136, compoundHCID 86741951HCID 86741951, compound

Product 1

HCID 19880121HCID 19880121, compound

Procedure

By methods outlined in Example 2 and using methyl-2-[3-cyclohexyl-1-propyl]acrylate was prepared methyl-1-benzyloxycarbonylaminoethyl-[2-carbomethoxy-5-cyclohexyl-1-n-pentyl]phosphinate. NMR (CDCl3) δ 0.8-3.1 (m, 23H); 3.6 (s, 3H); 3.6 (d, 3H); 3.6-4.2 (m, 1H); 5.0 (s, 2H); 5.2 (d, 0.5H); 5.5 (d, 0.5H); 7.2 (s, 5H).

Sources & evidence

ORD record
ord-9dd55dfd1cbb41909783e409435dda4c
Source dataset
uspto-grants-1987_12
Patent number
US04715994

Reaction notes

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