Succinic anhydride → HCID 15599104, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 1.50 g (0.0045 mole) of 2,6-di-tertiary-butyl-4-(3'-chloroanilino)phenol and 0.90 g (0.0090 mole) of succinic anhydride was heated under a nitrogen atmosphere at 140° C. for one hour. The resulting solid was recrystallized once from a mixture of ethanol and water and then twice from a mixture of ethyl acetate and hexane to hydroxyphenyl)-N-(3-chlorophenyl)carbamoyl]propionic acid, m.p. 204°-206° C. Analysis: Calculated for C24H30ClNO: % C, 66.7; % H, 7.0; % N, 3.2; Found: % C, 67.1; % H, 7.0; % N, 3.2.

Provenance & Evidence