HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Tolyl isocyanate → t-Butyl 3-methoxy-4-o-tolylureidophenylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Tolyl isocyanate | HCID 69194 | — |
| Reactant | HCID 22244730 | HCID 22244730 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | t-Butyl 3-methoxy-4-o-tolylureidophenylacetate | HCID 69645017 | 97.2% |
Reaction Steps
To a solution of t-butyl 4-amino-3-methoxyphenylacetate (0.024 g, 0.10 mmol) in methylene chloride (2.0 mL) was added o-tolyl isocyanate (15 μL, 0.12 mmol). The reaction was stirred for 2 h then concentrated to afford t-Butyl 3-methoxy-4-o-tolylureidophenylacetate (0.036 g, 97%) as a tan foam:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06630512B2 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-6a58242a11dc4c278910b4de1063b62d |
| Source note | uspto-grants-2003_10 |