HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-[4-(benzyloxy)phenyl]-2-ethoxyprop-2-enoate → Ethyl 2-ethoxy-3-(4-hydroxyphenyl)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-[4-(benzyloxy)phenyl]-2-ethoxyprop-2-enoate | HCID 54423854 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Ethyl 2-ethoxy-3-(4-hydroxyphenyl)propanoate | HCID 11791243 | 100.7% |
Reaction Steps
3-(4-Benzyloxyphenyl)-2-ethoxyacrylic acid ethyl ester (described in Example 38a) (62 g; 0.19 mole) was hydrogenated in ethyl acetate (400 ml) at atmospheric pressure using Pd/C (10%) as catalyst. The mixture was filtered through celite and evaporated in vacuo to give 45.6 g (yield 100%) of 2-ethoxy-3-(4-hydroxyphenyl)propanoic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06630600B1 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-ef5ca7b13bc448a29aa41efa4d2a645d |
| Source note | uspto-grants-2003_10 |