Ethyl 2-ethoxy-3-(4-hydroxyphenyl)propanoate → HCID 86595064, compound

HRID 987261Notes

Reaction equation

HRID 987261 reaction equation
[CH2:1]([O:3][C:4](=[O:17])[CH:5]([O:14][CH2:15][CH3:16])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1)[CH3:2].[CH3:18][S:19]([O:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[CH2:29][CH2:30][CH2:31][CH2:32]CS([O-])(=O)=O)(=[O:21])=[O:20]>>[CH2:1]([O:3][C:4](=[O:17])[CH:5]([O:14][CH2:15][CH3:16])[CH2:6][C:7]1[CH:8]=[CH:9][C:10]([O:13][CH2:32][CH2:31][CH2:30][CH2:29][C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=2[O:22][S:19]([CH3:18])(=[O:21])=[O:20])=[CH:11][CH:12]=1)[CH3:2]

Participants

3

Procedure

2-Ethoxy-3-{4-(4-(2-methanesulfonyloxyphenyl)butoxy]phenyl}propanoic acid ethyl ester was synthesized using the same method as in Example 1b from 2-ethoxy-3-(4-hydroxyphenyl)propanoic acid ethyl ester (described in Example 20b) and 4-(2-methanesulfonyloxyphenyl)butylmethanesulfonate.

Sources & evidence

ORD record
ord-79dcbd4e07084a219cebf567ae61a906
Source dataset
uspto-grants-2003_10
Patent number
US06630600B1

Reaction notes

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