1-(4-Tert-butylphenyl)-2-chloroethan-1-one → 2-[3-(3,4-Dichloro-phenyl)-1-(4-tert-butyl-phenacyl)-pyrrolidin-3-yl]-ethanol
Reaction equation
[C:17]([CH3:18])([CH3:19])([CH3:20])[c:21]1[cH:22][cH:23][c:24]([C:25]([CH2:26][Cl:27])=[O:28])[cH:29][cH:30]1.[Cl:1][c:2]1[cH:3][c:4]([C:9]2([CH2:14][CH2:15][OH:16])[CH2:10][NH:11][CH2:12][CH2:13]2)[cH:5][cH:6][c:7]1[Cl:8]>>[Cl:1][c:2]1[cH:3][c:4]([C:9]2([CH2:14][CH2:15][OH:16])[CH2:10][N:11]([CH2:26][C:25]([c:24]3[cH:23][cH:22][c:21]([C:17]([CH3:18])([CH3:19])[CH3:20])[cH:30][cH:29]3)=[O:28])[CH2:12][CH2:13]2)[cH:5][cH:6][c:7]1[Cl:8]Participants
3
Sources & evidence
- ORD record
- ord-33f0c0322fb34fc2a218c49f066f5bab
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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