Ethyl 3-[4-(benzyloxy)phenyl]-2-ethoxyprop-2-enoate → 3-(4-Benzyloxyphenyl)-2-ethoxypropanoic acid ethyl ester

関与物質

反応手順

3-(4-Benzyloxyphenyl)-2-ethoxyacrylic acid ethyl ester (described in Example 38a) (0.5 g; 1.5 mmole) was hydrogenated at atmospheric pressure using rhodium on charcoal (5%; 50 mg) as catalyst in methanol (20 ml). The crude product was purified by chromatography using heptane:ethyl acetate (5:1) as eluant to give 50 mg (yield 10%) of 3-(4-benzyloxyphenyl)-2-ethoxypropanoic acid ethyl ester.

情報源と証拠