HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Benzyloxyphenyl)-2-ethoxy-2-methyl propanoic acid ethyl ester → 2-Ethoxy-3-(4-hydroxyphenyl)2-methyl propanoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Benzyloxyphenyl)-2-ethoxy-2-methyl propanoic acid ethyl ester | HCID 54545739 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-Ethoxy-3-(4-hydroxyphenyl)2-methyl propanoic acid ethyl ester | HCID 53889157 | 99.7% |
Reaction Steps
3-(4-Benzyloxyphenyl)-2-ethoxy-2-methyl propanoic acid ethyl ester (0.34 g; 0.99 mmole) was hydrogenated for 18 hours at atmospheric pressure in ethyl acetate using Pd/C (0.05 g) as catalyst and then filtered through hyflo. The solvent was evaporated and 0.249 g (98% yield) of 2-ethoxy-3-(4-hydroxyphenyl)-2-methyl propanoic acid ethyl ester was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06630600B1 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-0459e2cd2a654b99a0042afa615237ce |
| Source note | uspto-grants-2003_10 |