Phenol → 3-(4-Benzyloxyphenyl)-2-phenoxypropanoic acid methyl ester

HRID 987322Notes

Reaction equation

HRID 987322 reaction equation
[CH3:1][O:2][C:3](=[O:21])[CH:4]([OH:20])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:8][CH:7]=1.[C:22]1(O)[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH3:1][O:2][C:3](=[O:21])[CH:4]([O:20][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:8][CH:7]=1

Participants

3

Reactant 2

HCID 996PhenolHCID 10493427Methyl 3-[4-(benzyloxy)phenyl]-2-hydroxypropanoate

Product 1

HCID 111322013-(4-Benzyloxyphenyl)-2-phenoxypropanoic acid methyl ester

Procedure

3-(4-Benzyloxyphenyl)-2-hydroxypropanoic acid methyl ester was reacted with phenol using the same method as in Example 38(c) to give 3-(4-benzyloxyphenyl)-2-phenoxypropanoic acid methyl ester.

Sources & evidence

ORD record
ord-2332171a1a714ebc99296f702d64d6b6
Source dataset
uspto-grants-2003_10
Patent number
US06630600B1

Reaction notes

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