2-(4-Methylsulfanylphenyl)ethanol → 3-{4-[2-(4-Methylsulfanylphenyl)ethoxy]phenyl}-2-phenoxy-propanoic acid methyl ester

HRID 987324Notes

Reaction equation

HRID 987324 reaction equation
[CH3:1][O:2][C:3](=[O:20])[CH:4]([O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=1.[CH3:21][S:22][C:23]1[CH:28]=[CH:27][C:26]([CH2:29][CH2:30]O)=[CH:25][CH:24]=1>>[CH3:1][O:2][C:3](=[O:20])[CH:4]([O:13][C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:30][CH2:29][C:26]2[CH:27]=[CH:28][C:23]([S:22][CH3:21])=[CH:24][CH:25]=2)=[CH:8][CH:7]=1

Participants

3

Reactant 2

HCID 27600862-(4-Methylsulfanylphenyl)ethanolHCID 178401663-(4-Hydroxyphenyl)-2-phenoxypropanoic acid methyl ester

Product 1

HCID 544550273-{4-[2-(4-Methylsulfanylphenyl)ethoxy]phenyl}-2-phenoxy-propanoic acid methyl ester

Procedure

3-(4-Hydroxyphenyl)-2-phenoxypropanoic acid methyl ester was reacted with 2-(4-methylsulfanylphenyl)ethanol using the same methods as in Example 38(c) to give 3-{4-[2-(4-methylsulfanylphenyl)ethoxy]phenyl}-2-phenoxy-propanoic acid methyl ester.

Sources & evidence

ORD record
ord-09a8e6bb870a43c4a91dc11c43fdd93f
Source dataset
uspto-grants-2003_10
Patent number
US06630600B1

Reaction notes

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