2-Propylphenol → HCID 18008628, compound
Reaction equation
[CH2:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[OH:10])[CH2:2][CH3:3].[CH3:11][CH2:12][CH2:13][CH2:14][CH:15]([CH:17]([CH3:19])C)C.[CH3:20][CH2:21]CC(CC(C)C)C.CC(CC(C(C)C)C)C>>[CH2:1]([C:4]1[CH:9]=[C:8]([CH2:20][CH2:21][CH2:19][CH2:17][CH2:15][CH2:14][CH2:13][CH2:12][CH3:11])[CH:7]=[CH:6][C:5]=1[OH:10])[CH2:2][CH3:3]Participants
3
Conditions
- Temperature
- 120 °C
Procedure
2-n-Propylphenol (5 mol, 681 g), dry Amberlyst 15 (50 g) and tripropylene (5.5 mol, 694 g, 951 ml) were placed in a 3000 ml 3N RBF. The mixture was heated and maintained at 120° C. under vigorous stirring for 7 hrs. After cooling to ambient temperature, the reaction mixture was filtered and distilled to obtain 2-n-propyl-4-nonylphenol in vacuo (135-150° C. at 0.5-2 T). Total 960 g of 2-n-propyl-4-nonylphenol was obtained as amber oils (71% yield with 95% plus purity).
Workup
- temperatureThe mixture was heated
- temperatureAfter cooling to ambient temperature
- filtrationthe reaction mixture was filtered
- distillationdistilled
Sources & evidence
- ORD record
- ord-a7a16e3ac25c45209671665bd8dbf545
- Source dataset
- uspto-grants-2003_10
- Patent number
- US06632410B2
Reaction notes
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