Hexahydro-1,4-diazepine → HCID 21891580, compound

HRID 987446Notes

Reaction equation

HRID 987446 reaction equation
[C:1]1([N:7]2[C:15]3[C:10](=[C:11]([O:20][CH3:21])[C:12]([O:18][CH3:19])=[C:13]([O:16][CH3:17])[CH:14]=3)[CH:9]=[C:8]2[C:22]([OH:24])=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH:25]1[CH2:31][CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1>>[C:1]1([N:7]2[C:15]3[C:10](=[C:11]([O:20][CH3:21])[C:12]([O:18][CH3:19])=[C:13]([O:16][CH3:17])[CH:14]=3)[CH:9]=[C:8]2[C:22]([N:25]2[CH2:31][CH2:30][CH2:29][N:28]([C:22]([C:8]3[N:7]([C:1]4[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=4)[C:15]4[C:10]([CH:9]=3)=[C:11]([O:20][CH3:21])[C:12]([O:18][CH3:19])=[C:13]([O:16][CH3:17])[CH:14]=4)=[O:24])[CH2:27][CH2:26]2)=[O:24])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 68163Hexahydro-1,4-diazepineHCID 21891630HCID 21891630, compound

Product 1

HCID 21891580HCID 21891580, compound

Procedure

1-Phenyl-4,5,6-trimethoxyindole-2-carboxylic acid (91 mg) and homopiperazine (14 mg) were reacted in the same manner as in Preparation Example 37 to obtain the title compound.

Sources & evidence

ORD record
ord-2ea2a760615d427f904bc3c8fe5ed9af
Source dataset
uspto-grants-2003_10
Patent number
US06632810B2

Reaction notes

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