HRID987446

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID68163

1H-1,4-Diazepine, hexahydro-

C5H12N2

结构：COc1cc2c(cc(C(=O)O)n2-c2ccccc2)c(OC)c1OC

HCID21891630

未命名化合物

PRODUCTS

生成物

结构：COc1cc2c(cc(C(=O)N3CCCN(C(=O)c4cc5c(OC)c(OC)c(OC)cc5n4-c4ccccc4)CC3)n2-c2ccccc2)c(OC)c1OC

HCID21891580

未命名化合物

PROCEDURE

实验过程

1-Phenyl-4,5,6-trimethoxyindole-2-carboxylic acid (91 mg) and homopiperazine (14 mg) were reacted in the same manner as in Preparation Example 37 to obtain the title compound.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2ea2a760615d427f904bc3c8fe5ed9af
来源数据集: uspto-grants-2003_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06632810B2
来源说明: uspto-grants-2003_10

反应 SMILES

[C:1]1([N:7]2[C:15]3[C:10](=[C:11]([O:20][CH3:21])[C:12]([O:18][CH3:19])=[C:13]([O:16][CH3:17])[CH:14]=3)[CH:9]=[C:8]2[C:22]([OH:24])=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH:25]1[CH2:31][CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1>>[C:1]1([N:7]2[C:15]3[C:10](=[C:11]([O:20][CH3:21])[C:12]([O:18][CH3:19])=[C:13]([O:16][CH3:17])[CH:14]=3)[CH:9]=[C:8]2[C:22]([N:25]2[CH2:31][CH2:30][CH2:29][N:28]([C:22]([C:8]3[N:7]([C:1]4[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=4)[C:15]4[C:10]([CH:9]=3)=[C:11]([O:20][CH3:21])[C:12]([O:18][CH3:19])=[C:13]([O:16][CH3:17])[CH:14]=4)=[O:24])[CH2:27][CH2:26]2)=[O:24])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1