alpha-Naphthyl isocyanate → HCID 12083619, compound

HRID 987486Notes

Reaction equation

HRID 987486 reaction equation
Cl.[NH2:2][CH2:3][C:4]1[CH:8]=[CH:7][N:6]([C:9]2[CH:18]=[C:17]3[C:12]([NH:13][C:14](=[O:24])[CH:15]([C:19]([O:21]CC)=[O:20])[NH:16]3)=[CH:11][C:10]=2[Cl:25])[CH:5]=1.[C:26]1([N:36]=[C:37]=[O:38])[C:35]2[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=2)[CH:29]=[CH:28][CH:27]=1>>[Cl:25][C:10]1[CH:11]=[C:12]2[C:17](=[CH:18][C:9]=1[N:6]1[CH:7]=[CH:8][C:4]([CH2:3][NH:2][C:37]([NH:36][C:26]3[C:35]4[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=4)[CH:29]=[CH:28][CH:27]=3)=[O:38])=[CH:5]1)[N:16]=[C:15]([C:19]([OH:21])=[O:20])[C:14](=[O:24])[NH:13]2

Participants

3

Reactant 2

HCID 66589alpha-Naphthyl isocyanateHCID 18008893HCID 18008893, compound

Product 1

HCID 12083619HCID 12083619, compoundYield 22.5%

Procedure

Using the compound (200 mg, 519 μmol) of Example 5 and 1-naphthyl isocyanate (89.4 μl, 622 μmol) and through the process similar to Example 38, 57.1 mg of title compound were obtained as yellowish brown powder. Yield 22%.

Sources & evidence

ORD record
ord-57e63db6768c4d38907f5861897ef54b
Source dataset
uspto-grants-2003_10
Patent number
US06632813B1

Reaction notes

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