Methyl 1-hydrazinothiocarbonylpiperidine-4-carboxylate → Methyl 1-[[1-[4-hydroxy-1-methyl-5-[4-(trifluoromethyl)phenyl]pyrazol-3-yl]ethylideneamino]carbamothioyl]piperidine-4-carboxylate

HRID 98754Notes

Reaction equation

HRID 98754 reaction equation
[NH:21]([NH2:22])[C:23](=[S:24])[N:25]1[CH2:26][CH2:27][CH:28]([C:31](=[O:32])[O:33][CH3:34])[CH2:29][CH2:30]1.[OH:1][c:2]1[c:3]([C:18]([CH3:19])=[O:20])[n:4][n:5]([CH3:17])[c:6]1-[c:7]1[cH:8][cH:9][c:10]([C:13]([F:14])([F:15])[F:16])[cH:11][cH:12]1>>[OH:1][c:2]1[c:3]([C:18]([CH3:19])=[N:22][NH:21][C:23](=[S:24])[N:25]2[CH2:26][CH2:27][CH:28]([C:31](=[O:32])[O:33][CH3:34])[CH2:29][CH2:30]2)[n:4][n:5]([CH3:17])[c:6]1-[c:7]1[cH:8][cH:9][c:10]([C:13]([F:14])([F:15])[F:16])[cH:11][cH:12]1

Participants

3

Reactant 2

HCID 24855846Methyl 1-hydrazinothiocarbonylpiperidine-4-carboxylateHCID 602067901-[4-hydroxy-1-methyl-5-(4-trifluoromethylphenyl)-1H-pyrazol-3-yl]ethanone

Product 1

HCID 86635886Methyl 1-[[1-[4-hydroxy-1-methyl-5-[4-(trifluoromethyl)phenyl]pyrazol-3-yl]ethylideneamino]carbamothioyl]piperidine-4-carboxylate

Sources & evidence

ORD record
ord-47f202ab5d97424284938d818914e592
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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