反应详情

温度

25 °C

2,6-Dichlorophenylthiourea (3.0 g, 13.6 mmol) was dissolved in 50 mL of dry methanol and dimethyl acetylenedicarboxylate (13.8 mmol, 1.7 mL) was added over a 10-minute period. The mixture was stirred at 25° C. for 40 minutes, then the mixture was heated at 55° C. for 3 hours. The solvent was removed by rotvap, and the crude product was recrystallized from methanol to yield the desired product.

1. temperaturethe mixture was heated at 55° C. for 3 hours
2. customThe solvent was removed by rotvap
3. customthe crude product was recrystallized from methanol