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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 987602Generated: October 31, 2026

Ethyl Acetate → HCID 18009475, compound

https://huagongshe.com/reaction/987602

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetateHCID 8857—
ReactantHCID 68834656HCID 68834656—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
ProductHCID 18009475HCID 18009475—

Reaction Steps

A mixture of 1-carboxymethylidenyl-4-phenyl-4-(3-(2-methoxyphenyl)-3-oxo-2-azaprop-1-yl)-cyclohexane (Example 174, 64 mg, 0.17 mmol) and Pd/C (10 mg, 10%), in 5.0 mL of EtOAc was shaken under 50 psi of hydrogen for 24 h. The mixture was filtered through a plug of silica gel and concentrated to give the title compound as a mixture of isomers.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06632836B1
Source datasetuspto-grants-2003_10
ORD IDord-d4d15155aadf40408685c383ee36f3e0
Source noteuspto-grants-2003_10