HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl bromoacetate → N-(3,4-dichlorophenyl)alanine Tert-butyloxycarbonylmethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl bromoacetate | HCID 79177 | — |
| Reactant | N-(3,4-dichlorophenyl)alanine | HCID 5491659 | — |
| Product | N-(3,4-dichlorophenyl)alanine Tert-butyloxycarbonylmethyl Ester | HCID 54406316 | — |
Reaction Steps
Following General Procedure AE above and using N-(3,4-dichlorophenyl)alanine (from Example AB above) and tert-butyl bromoacetate (Aldrich), the title compound was prepared as a solid. The reaction was monitored by silica gel tlc (Rf=0.57 in 25% EtOAc/hexanes). Purification was by recrystallization from ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06632811B2 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-b6cd35ca7e58469db1966f2ce145fdb1 |
| Source note | uspto-grants-2003_10 |