反应详情

1.81 g (5.40 mmol) of methyl (triphenylphosphoranylidene)acrylate are added, at room temperature, to a solution of 1.0 g (5.15 mmol) of 3,4-diethoxybenzaldehyde and 10 ml of toluene. The reaction is then allowed to proceed for 1 hour at room temperature, the reaction suspension is clarified by filtration over a silica gel bed and the filtrate is evaporated down. Chromatography of the residue over silica gel using toluene/ethyl acetate gives methyl 3(E)-(3,4-diethoxyphenyl)acrylate.

1. filtrationthe reaction suspension is clarified by filtration over a silica gel bed
2. customthe filtrate is evaporated down