Potassium Hydroxide → HCID 22987086, compound

HRID 987878Notes

Reaction equation

HRID 987878 reaction equation
[CH2:1]([O:3][C:4]1[CH:9]=[C:8](/[CH:10]=[CH:11]/[C:12]([O:14]C)=[O:13])[CH:7]=[CH:6][C:5]=1[C:16]1[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=1)[CH3:2].[OH-].[K+]>CO.O>[CH2:1]([O:3][C:4]1[CH:9]=[C:8](/[CH:10]=[CH:11]/[C:12]([OH:14])=[O:13])[CH:7]=[CH:6][C:5]=1[C:16]1[CH:17]=[CH:18][C:19]([O:22][CH3:23])=[CH:20][CH:21]=1)[CH3:2]

Participants

5

Reactant 2

HCID 14797Potassium HydroxideHCID 22987081HCID 22987081, compound

Product 1

HCID 22987086HCID 22987086, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

The preparation is carried out analogously to Example 2 from 1.0 g (3.2 mmol) of methyl 3(E)-(2-ethoxy-4′-methoxybiphenyl-4-yl)acrylate, 50 ml of a 10% solution of potassium hydroxide in methanol and 2 ml of water and gives 3(E)-(2-ethoxy-4′-methoxybiphenyl-4-yl)acrylic acid.

Sources & evidence

ORD record
ord-25cd2d358ae9429b8334d90aff7f4cb3
Source dataset
uspto-grants-2003_10
Patent number
US06632909B2

Reaction notes

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