HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → glucopyranose pentabenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal | HCID 107526 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | glucopyranose pentabenzoate | HCID 11456758 | — |
Reaction Steps
100 g of D-glucose (555 mmol; 1 eq) are dissolved in 2 l of pyridine and the reaction medium is heated under reflux for 1 hour before 387 ml (3,330 mmol; 6 eq) of benzoyl chloride are added thereto in the hot. After addition, the medium is diluted with water, the product precipitates and is filtered off and rinsed with water to neutrality. After drying, it is purified by recrystallisation from ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06632940B1 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-943c3a5f4c9e4fe7b8b657c828aace41 |
| Source note | uspto-grants-2003_10 |