HCID 12986171, compound → HCID 513936, compound

Participants

Reaction Steps

The title compound was prepared from (1S,4S)-(1-{4-[(4-amino-benzenesulfonyl)-isobutyl-amino]-5-hydroxy-pentylcarbamoyl}-2-biphenyl-2-yl-ethyl)-carbamic acid tert-butyl ester as described for the acid hydrolysis of (1S,5S)-(1-{5-[(4-amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2-naphthalen-2-yl-ethyl)-carbamic acid tert-butyl ester (see example 49). The final product was obtained in 90% yield.

Provenance & Evidence