HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 513949, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | tert-Butyl bromoacetate | HCID 79177 | — |
| Reactant | HCID 513930 | HCID 513930 | — |
| Product | HCID 513949 | HCID 513949 | — |
Reaction Steps
The title compound was prepared from (2S,4S)-2-amino-N-{4-[(4-amino-benzenesulfonyl)-isobutyl-amino]-5-hydroxy-pentyl}-3-naphthalen-1-yl-propionamide (product of example 8) using tert-butyl bromoacetate. The final product was hydrolysed using lithium hydroxide to obtain the acid in 74% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06632816B1 |
| Source dataset | uspto-grants-2003_10 |
| ORD ID | ord-0ec5ef67952f49539efaf4d6f90b8ed0 |
| Source note | uspto-grants-2003_10 |