Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 987965Generated: October 25, 2026

(S)-2-methoxycarbonylamino-3,3-diphenyl-propionic acid → Ppl-100

https://huagongshe.com/reaction/987965

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-methoxycarbonylamino-3,3-diphenyl-propionic acidHCID 10017620—
Reactant(1S)-4-amino-N-(5-amino-1-hydroxymethyl-pentyl)-N-isobutyl-benzenesulfonamideHCID 20595420—
ProductPpl-100HCID 513956—

Reaction Steps

The title compound was prepared from (1S)-4-amino-N-(5-amino-1-hydroxymethyl-pentyl)-N-isobutyl-benzenesulfonamide (XII) (example 28, step D) as described in general procedure B using (2S)-2-methoxycarbonylamino-3,3-diphenyl-propionic acid (step A). The final product was obtained in 67% yield (121 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06632816B1
Source datasetuspto-grants-2003_10
ORD IDord-12c80c89f857458ab322c25173d56050
Source noteuspto-grants-2003_10