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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 987986Generated: October 30, 2026

Nicotinic Acid → HCID 513995, compound

https://huagongshe.com/reaction/987986

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNicotinic AcidHCID 938—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 513994HCID 513994—
ProductHCID 513995HCID 513995—

Reaction Steps

The title compound was then obtained in 65% yield using (2S,5S)-2-amino-N-{5-[(4-amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexyl}-3,3-diphenyl-propionamide (product of example 72) and nicotinic acid with general procedure A. However, 1.0N NaOH was used instead of 1.0N hydrochloric acid for the preparation of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06632816B1
Source datasetuspto-grants-2003_10
ORD IDord-d7403c5c495142e4862ecf34ecd9a3f7
Source noteuspto-grants-2003_10