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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 987987Generated: October 30, 2026

Isonicotinic Acid → HCID 513996, compound

https://huagongshe.com/reaction/987987

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsonicotinic AcidHCID 5922—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 513994HCID 513994—
ProductHCID 513996HCID 513996—

Reaction Steps

The title compound was then obtained in 76% yield using (2S,5S)-2-amino-N-{5-[(4-amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexyl}-3,3-diphenyl-propionamide (product of example 72) and isonicotinic acid with general procedure A. However, 1.0N NaOH was used instead of 1.0N hydrochloric acid for the preparation of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06632816B1
Source datasetuspto-grants-2003_10
ORD IDord-b6e73dce0dd049d998e8c8ca18b5ccd4
Source noteuspto-grants-2003_10