HCID 70006697, compound → HCID 69792726, compound

HRID 988031Notes

Reaction equation

HRID 988031 reaction equation
[CH3:1][O:2]C1C=CC(C#CC(OCC)=O)=C(OC)C=1C1C(C)=CC2C(C)(C)CCC(C)(C)C=2C=1.[CH3:33][O:34][C:35]1[CH:40]=[CH:39][C:38]([C:41]#[C:42][C:43]([OH:45])=[O:44])=[C:37](OC)[C:36]=1[C:48]1[C:57]([CH3:58])=[CH:56][C:55]2[C:54]([CH3:60])([CH3:59])[CH2:53][CH2:52][C:51]([CH3:62])([CH3:61])[C:50]=2[CH:49]=1>>[CH3:1][O:2][CH2:33][O:34][C:35]1[CH:40]=[CH:39][C:38]([C:41]#[C:42][C:43]([OH:45])=[O:44])=[CH:37][C:36]=1[C:48]1[C:57]([CH3:58])=[CH:56][C:55]2[C:54]([CH3:59])([CH3:60])[CH2:53][CH2:52][C:51]([CH3:62])([CH3:61])[C:50]=2[CH:49]=1

Participants

3

Reactant 2

HCID 70006697HCID 70006697, compoundHCID 86759218HCID 86759218, compound

Product 1

HCID 69792726HCID 69792726, compound

Procedure

In a manner similar to that of Example 2(h), starting from 439 mg (1 mmol) of ethyl [4-methoxy-methoxy-3-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)phenyl]propynoate, 375 mg (91%) of [4-methoxy-methoxy-3-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)phenyl]propynoic acid having a melting point of 168°-170° C. were obtained.

Workup

  1. customwere obtained

Sources & evidence

ORD record
ord-bf98c5e4bb7548b9b5d5628bb8cc74c9
Source dataset
uspto-grants-2003_10
Patent number
US06632963B1

Reaction notes

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