(3,5-Di-tert-butyl-2-propoxyphenyl)boronic acid → 3-(3',5'-di-tert-butyl-6-methoxy-2'-propoxy-3-biphenylyl)acrylic Acid

Participants

Reaction Steps

In a manner similar to that of Example 1(c), by reaction of 1.0 g (3.5 mmol) of ethyl 3-(3-bromo-4-methoxyphenyl)acrylate obtained in Example 13(d) with 1.54 g (5.26 mmol) of 2-propyloxy-3,5-di-tert-butylphenylboronic acid obtained in Example 39(b), 1.20 g (76%) of the expected compound was obtained in the form of a white powder having a melting point of 107°-109° C.

Provenance & Evidence