Thiophene-3-boronic acid → 6-(Thiophen-3-yl)-1H-indazole

HRID 988104Notes

Reaction equation

HRID 988104 reaction equation
I[C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[N:7][NH:8]2)=[CH:4][CH:3]=1.[S:11]1[CH:15]=[CH:14][C:13](B(O)O)=[CH:12]1>>[S:11]1[CH:15]=[CH:14][C:13]([C:2]2[CH:10]=[C:9]3[C:5]([CH:6]=[N:7][NH:8]3)=[CH:4][CH:3]=2)=[CH:12]1

Participants

3

Reactant 2

HCID 581760Thiophene-3-boronic acidHCID 129912416-iodo-1H-indazole

Product 1

HCID 180074976-(Thiophen-3-yl)-1H-indazole

Procedure

(237 mg, 71%); from 6-iodo-1H-indazole (403.5 mg, 1.65 mmol) and 3-thiopheneboronic acid (236.5 mg, 1.8 mmol).

Sources & evidence

ORD record
ord-727d12e0c6954df48f3248694a7de5d6
Source dataset
uspto-grants-2003_10
Patent number
US06635639B2

Reaction notes

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