Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 4-Pyridin-4-yl-1,3-dihydro-indol-2-one | HCID 12111581 | — |
| Reactant | 3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrole-2-carbaldehyde | HCID 12111582 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67016918 | HCID 67016918 | — |
Reaction Steps
A mixture of 4-pyridin-4-yl-1,3-dihydroindol-2-one (50 mg, 0.24 mmol), 3,5-dimethyl-4-(4-methyl-piperazine-1-carbonyl)-1H-pyrrole-2-carbaldehyde (59 mg, 0.24 mmol) and piperidine (0.1 mL) in ethanol (1 mL) was heated at 60° C. for 5 hours. The reaction was concentrated and the residue was column chromatographed to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06635640B2 |
|---|
| Source dataset | uspto-grants-2003_10 |
|---|
| ORD ID | ord-6217a3cb39d24eb8af4d16ffb37d7b46 |
|---|
| Source note | uspto-grants-2003_10 |
|---|
